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  • Title: [Demonstration of an interferon alpha receptor in human colonic cancer cells in culture].
    Author: Boissard C, Chelbi Alix MK, Gali P, Thang MN, Rosselin G.
    Journal: C R Acad Sci III; 1989; 309(11):485-92. PubMed ID: 2533880.
    Abstract:
    The IFN-alpha 2 receptor present in human cancerous colonic cells in culture has a capacity of 1,800 sites per cell with a kd of 0.5 nM. The molecular mass of the interferon alpha 2 (IFN-alpha 2) receptor complex is 134 kd. The IFN-alpha 2 induces the activity of the 2'5' oligoadenylate (2'5' A) synthetase activity in these cells and partly inhibits their growth.
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