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  • Title: Chronic intestinal pseudo-obstruction due to lymphocytic intestinal leiomyositis: Case report and literature review.
    Author: Uchida K, Otake K, Inoue M, Koike Y, Matsushita K, Araki T, Okita Y, Tanaka K, Uchida K, Yodoya N, Iwamoto S, Arai K, Kusunoki M.
    Journal: Intractable Rare Dis Res; 2012 Feb; 1(1):35-9. PubMed ID: 25343071.
    Abstract:
    Lymphocytic intestinal leiomyositis is a rare entity, which causes chronic intestinal pseudo-obstruction (CIPO) in children. We present the first case of a boy who had pure red cell anemia 1 year before onset. Prolonged ileus developed after gastroenteritis and the patient was diagnosed using a biopsy of the intestinal wall. Findings from the present case indicate that there are three important factors for accurate diagnosis: history of enteritis, positive serum smooth muscle antibody, and lymphocyte infiltration with muscle destruction in the muscularis propria in the intestinal wall. Earlier diagnosis and induction of immunosuppressive therapy may be essential for a better outcome.
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