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  • Title: [The effect of nicotinamide and nicotinic and ascorbic acids on the penicillin concentration in the blood serum and tissues of rabbits].
    Author: Bednova VN, Rotanov SV, Navolotskaia TI, Milonova TI, Orlina EA.
    Journal: Vestn Dermatol Venerol; 1989; (12):20-3. PubMed ID: 2534453.
    Abstract:
    Measurements of penicillin concentrations in the blood sera and tissues of rabbits have revealed a reduction of this antibiotic levels as the doses of injected ascorbic acid grew. A combination of benzylpenicillin with ascorbic and nicotinic acids improved penicillin penetration into experimental animals' tissues.
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