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  • Title: Silver(I)-catalyzed annulation for the regioselective synthesis of N-imino-γ-carbolinium ylides from hydrazones of indole-3-carbonyl derivatives and propargylic alcohols.
    Author: Zhu Y, Shen XR, Tang HT, Lin M, Zhan ZP.
    Journal: Org Biomol Chem; 2014 Dec 21; 12(47):9514-8. PubMed ID: 25350455.
    Abstract:
    A regioselective efficient synthetic approach to N-imino-γ-carbolinium ylides via AgOTf-catalyzed iminoannulation has been developed. This transformation proceeds via a silver(i) triflate-catalyzed consecutive Friedel-Crafts reaction/N-C bond formation sequence between the readily available indole derivatives and propargylic alcohols.
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