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  • Title: The bovine papillomavirus type 1 transcriptional activator E2 protein binds to its DNA recognition sequence as a dimer.
    Author: Moskaluk CA, Bastia D.
    Journal: Virology; 1989 Mar; 169(1):236-8. PubMed ID: 2538035.
    Abstract:
    The transcriptional trans-activator E2 protein from bovine papillomavirus type 1 has been shown to bind to the DNA consensus sequence ACCN6GGT. We have produced the DNA-binding domain of the E2 protein as a recombinant protein in Escherichia coli. The E2 DNA-binding domain was purified as two different molecular weight forms. Using these purified proteins, we show that two molecules of the E2 protein bind to a single DNA consensus binding site.
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