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  • Title: [Presynaptic action of tubocurarine during frequent stimulation of a motor nerve].
    Author: Grigor'ev VM, Danilov AF, Skliarov AI.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1989 Jan; 75(1):28-32. PubMed ID: 2538372.
    Abstract:
    The dependence of the end-plate potentials inhibition upon the prevention of the muscle twitches either by tubocurarine, or alpha-neurotoxin, or cutting of the fibers was studied during nerve tetanization in the frog isolated cutaneous pectoral muscles. The decrease in end-plate potentials in the course of tetanization was the strongest under the effect of tubocurarine. The latter seems to inhibit the quantum release of acetylcholine during the nerve tetanization.
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