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  • Title: An age-period-cohort analysis of cancer incidence among the oldest old, Utah 1973-2002.
    Author: Hanson HA, Smith KR, Stroup AM, Harrell CJ.
    Journal: Popul Stud (Camb); 2015; 69(1):7-22. PubMed ID: 25396304.
    Abstract:
    We used age-period-cohort (APC) analyses to describe the simultaneous effects of age, period, and cohort on cancer incidence rates in an attempt to understand the population dynamics underlying their patterns among those aged 85+. Data from the Utah Cancer Registry (UCR), the US Census, the National Center for Health Statistics (NCHS), and the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) programme were used to generate age-specific estimates of cancer incidence at ages 65-99 from 1973 to 2002 for Utah. Our results showed increasing cancer incidence rates up to the 85-89 age group followed by declines at ages 90-99 when not confounded by the separate influences of period and cohort effects. We found significant period and cohort effects, suggesting the role of environmental mechanisms in cancer incidence trends between the ages of 85 and 100.
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