These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A denaturation-induced proton-uptake study of horse ferricytochrome c.
    Author: Hartshorn RT, Moore GR.
    Journal: Biochem J; 1989 Mar 01; 258(2):595-8. PubMed ID: 2539812.
    Abstract:
    The observation that 6 M-urea denatures horse ferricytochrome c in the pH range 4-6, but not horse ferrocytochrome c, has been exploited to determine the denaturation-induced proton uptake of ferricytochrome c. This is related to the pKa values of ionizable groups buried within the native protein. The data indicate that one of the haem propionic acid substituents of ferricytochrome c has a pKa of less than 4.5, whereas the other has a pKa of greater than 9.
    [Abstract] [Full Text] [Related] [New Search]