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  • Title: Functional role of bdm during flagella biogenesis in Escherichia coli.
    Author: Kim JS, Kim YJ, Seo S, Seong MJ, Lee K.
    Journal: Curr Microbiol; 2015 Mar; 70(3):369-73. PubMed ID: 25398323.
    Abstract:
    The biofilm-dependent modulation gene (bdm) has recently been shown to play a role in osmotic-induced formation of biofilm in Escherichia coli. In this study, we demonstrated that deletion of bdm results in down-regulation of flagella biosynthesis genes and, consequently, a defect in E. coli motility. In addition, we employed atomic force microscopy to confirm the absence of flagella-like structures on the surface of bdm-null cells. These findings indicate that bdm plays a key role in regulatory pathway for the formation of flagella.
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