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  • Title: [5'-nucleotidase activity in the blood in chronic diseases of the liver and biliary tract].
    Author: Loginov AS, Isakova ZS, Skobeleva TV, Kartashova NA.
    Journal: Sov Med; 1989; (1):10-2. PubMed ID: 2541511.
    Abstract:
    Assessment of 5'-Nuc activity in 86 patients with diffuse hepatic diseases with and without cholestasis, mechanical jaundice of varying origins, and 20 donors has demonstrated the sensitivity of this test. High 5'-Nuc activity was seen in cases of chronic hepatic lesions with cholestasis and mechanical jaundice due to cancer of the prostatic head. A moderate 5'-Nuc rise was seen in casts of choledocholithiasis and active cirrhosis without cholestasis. Different correlations seen in the examined groups, in comparison to other cholestatic parameters, make it possible to use serum 5'-Nuc determination as an independent test.
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