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  • Title: [Evaluation of the cardiac and peripheral vascular effects of the administration of single-dose enalapril and captopril in essential arterial hypertension].
    Author: Longhini C, Ansani L, Musacci GF, Vaccari M, Fraccaroli GP, Mele D, Aggio S, Baracca E.
    Journal: Cardiologia; 1989 Jan; 34(1):61-7. PubMed ID: 2541907.
    Abstract:
    The effects of single orally-administered dose of enalapril and captopril on central and district-peripheral circulations have been studied in 20 patients with essential arterial hypertension. Either drug caused a decrease in arterial pressure, telesystolic and telediastolic parietal stress, and a reduction in the peripheral vascular resistance of upper limb district. Furthermore, at the upper limb district level, increases in arterial flow and venous-system capacity have been observed. The entity of these modifications induced by enalapril and captopril appeared comparable, according to the respective peak-time and used dosages. Under this study conditions, the difference between the drugs resulted to be essentially of chronological nature.
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