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  • Title: Pd-Catalyzed direct C-H functionalization of imidazolones with aryl- and alkenyl halides.
    Author: Muselli M, Baudequin C, Hoarau C, Bischoff L.
    Journal: Chem Commun (Camb); 2015 Jan 14; 51(4):745-8. PubMed ID: 25420541.
    Abstract:
    Direct C-H arylation and alkenylation of 4,4'-dialkylimidazolones with a broad range of halides under palladium and copper catalysis have been developed. This methodology is applied to the preparation of recently discovered fatty acid synthetase (FAS) inhibitors.
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