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  • Title: [Pulmonary alveolar microlithiasis: Report of one case].
    Author: Fernández F C, Salinas F M, de Grazia K JA, Díaz P JC.
    Journal: Rev Med Chil; 2014 May; 142(5):656-61. PubMed ID: 25427025.
    Abstract:
    Pulmonary alveolar microlithiasis is an extremely rare disease characterized by intra-alveolar accumulation of calcified spherical particles (called microliths), due to a mutation of the gene encoding a membrane transport protein of the alveolar surface. Most patients are asymptomatic at diagnosis. The course of the disease is slowly progressive, with development of pulmonary fibrosis and respiratory failure. The "sandstorm" pattern is the characteristic finding of this disease. We report a 39-year-old female presenting with progressive dyspnea. A chest X ray showed ground-glass opacities and a high resolution CT scan showed numerous calcified lung micronodules. A surgical lung biopsy confirmed the diagnosis of pulmonary alveolar microlithiasis.
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