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  • Title: A new type of toxin A-negative, toxin B-positive Clostridium difficile strain lacking a complete tcdA gene.
    Author: Janezic S, Marín M, Martín A, Rupnik M.
    Journal: J Clin Microbiol; 2015 Feb; 53(2):692-5. PubMed ID: 25428159.
    Abstract:
    Toxins A and B are the main virulence factors of Clostridium difficile and are the targets for molecular diagnostic tests. Here, we describe a new toxin A-negative, toxin B-positive, binary toxin CDT (Clostridium difficile transferase)-negative (A(-) B(+) CDT(-)) toxinotype (XXXII) characterized by a variant type of pathogenicity locus (PaLoc) without tcdA and with atypical organization of the PaLoc integration site.
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