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  • Title: A High-Sensitivity Coumarin-Based Fluorescent Probe for Monitoring Hydrogen Sulfide in Living Cells.
    Author: Qiu Q, Deng X, Jiao L, Zhao T, Meng F, Huang W, Qian H.
    Journal: Chem Biol Drug Des; 2015 Aug; 86(2):173-9. PubMed ID: 25430778.
    Abstract:
    A novel coumarin-based fluorescence probe has been constructed for the selective and sensitive detection of hydrogen sulfide (H2 S). This probe displays high sensitivity and linearity to H2 S in degassed PBS buffers and fetal bovine serum. It reacts with H2 S with high selectivity over Cys, GSH, and other anions. Meanwhile, successful detection of H2 S in living cells was also demonstrated.
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