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  • Title: Antioxidant enzyme activities in heart and skeletal muscle of rats of different ages.
    Author: Vertechy M, Cooper MB, Ghirardi O, Ramacci MT.
    Journal: Exp Gerontol; 1989; 24(3):211-8. PubMed ID: 2543589.
    Abstract:
    The activity of antioxidant enzymes was measured in cardiac and skeletal muscle in rats aged either 4, 15, or 27 months. Generally, regardless of age, heart contains a greater content of these enzymes than skeletal muscle. Whereas skeletal muscle showed age-dependent increases in glutathione peroxidase, glutathione reductase, and catalase activities, heart tissue showed increases in only the glutathione peroxidase activity. Neither tissue showed any significant age-dependent change in cytosolic or mitochondrial superoxide dismutase content or in cytochrome oxidase.
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