These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [An analysis of the action of nonspecific and restriction nucleases on metaphase chromosomes in situ].
    Author: Smirnov AF, Patkin EL, Stefanova VN, Chiriaeva OG, Sorokin AV.
    Journal: Tsitologiia; 1989 Feb; 31(2):182-8. PubMed ID: 2544048.
    Abstract:
    Patterns of differential staining of Drosophila, mouse, rat, cattle and pig chromosomes were examined after the treatment with nucleases (DNAase I, DNAase II) and restriction enzymes (AluI, HpaII, MspI, BpE, EcoRI). The above effects depend on the species used, on the enzymes and substitution of thymine for bromodeoxyuridine in the chromosomal DNA. It is supposed that such a phenomenon may not only result from the irregular distribution of specific restriction sites along chromosomes but also depend on the specificity of supramolecular organization of the chromosomal DNA.
    [Abstract] [Full Text] [Related] [New Search]