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  • Title: [AIDS-related primary CNS non-Hodgkin's lymphoma in a patient with previous Epstein-Barr virus panuveitis. A clinico-pathological report].
    Author: Ruiz-Bilbao S, Hernández À, Gómez-Sánchez S, Romeu J, Llobera L L, Carrato C, Anglada R, Sabala A, Matas L.
    Journal: Arch Soc Esp Oftalmol; 2015 May; 90(5):241-3. PubMed ID: 25443210.
    Abstract:
    CLINICAL CASE: Patient with AIDS and Epstein-Barr virus (EBV) uveitis. The PCR of the aqueous and vitreous humor was positive for EBV, and DNA quantification was 56.602×10(6) copies/ml in the vitreous humor, 173,400 copies/ml in the peripheral blood, and negative in the cerebrospinal fluid (CSF). The patient developed a non-Hodgkin's lymphoma (NHL), diagnosed in the autopsy. CONCLUSION: The EBV is a rare cause of uveitis and it may be necessary to perform a quantitative PCR to reach the diagnosis. High amounts of EBV DNA are associated with a greater incidence of NHL.
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