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  • Title: [Status of the hypophyseo-adrenal system and functional morphology of the adrenal glands in residents of Northern European areas of the USSR].
    Author: Sukhanov SG, Tkachev AV.
    Journal: Arkh Patol; 1989; 51(4):58-62. PubMed ID: 2545185.
    Abstract:
    Serum corticotropin and cortisol levels were measured in 20-40-year old healthy residents (144 males and 361 females) in the North. A functional Synacthen Depot test was performed in 5 volunteers. The adrenal glands from 56 males and 8 females of the same age who had died from accidents were pathohistologically and stereometrically examined. The signs of functional tension were established in the pituitary-adrenal cortex system. The Synacthen Depot test determined sufficient potentials of the organ to show responses to specific stimulation. Morphologically, a number of changes were found, which might be regarded as a prerequisite to the development of functional and pathological disturbances in the above-mentioned link of the endocrine system.
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