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  • Title: Evaluation and management of hepatocellular carcinoma.
    Author: Kulik LM, Chokechanachaisakul A.
    Journal: Clin Liver Dis; 2015 Feb; 19(1):23-43. PubMed ID: 25454295.
    Abstract:
    The burden of hepatocellular carcinoma is rising and anticipated to escalate and while the best chance for long term cure remains transplantation, however the shortage of available organs remains a limitation. Liver directed therapy can serve the role of bridge/downstaging to transplant or as palliative care. Despite an improved overall survival among patients with HCC, due to advancements in surgical techniques, liver directed and systemic therapy, the 5 year overall survival remains low at 18% high-lightening the need for novel therapies. Surveillance for HCC is key to detect disease at an early stage to increase the chances for a potentially curative option.
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