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  • Title: Diels-Alder adducts with PTP1B inhibition from Morus notabilis.
    Author: Wang M, Gao LX, Wang J, Li JY, Yu MH, Li J, Hou AJ.
    Journal: Phytochemistry; 2015 Jan; 109():140-6. PubMed ID: 25457492.
    Abstract:
    Eight Diels-Alder adducts, morbilisins A-H (1-8), a known analogue, chalcomoracin (9), together with eleven known flavonoids and 2-arylbenzofurans, were isolated from the leaves of Morus notabilis. Their structures were elucidated by extensive spectroscopic analysis, including 1D, 2D NMR, MS, and ECD data. Compounds 1, 5, and 7-9 showed inhibition against PTP1B phosphatase activity in vitro.
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