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  • Title: [Application of transbronchial brushing for histological diagnosis of lung cancer].
    Author: Yamakama H, Baba M, Shiba M, Urabe N, Fujisawa T, Yamaguchi Y, Oiwa T.
    Journal: Nihon Kyobu Shikkan Gakkai Zasshi; 1989 Jan; 27(1):64-70. PubMed ID: 2545965.
    Abstract:
    In order to improve the preoperative diagnostic rate of lung cancer, histological examination was performed by transbronchial brushing in 35 cases, and diagnostic contribution of brushing specimen was compared with that of transbronchial forceps biopsy (TBFB). Histological structures were well preserved in the histology section of brushing specimens, especially in cases of small cell lung cancer. The positive rate of brushing histology was 46%, which was the same as that of TBFB. The total histological diagnostic rate was 66% with simultaneous examination of bronchial brushing and TBFB specimens. Consequently, the use of brushing specimens for histologic evaluation made an additional contribution to the correct positive histology diagnostic rate. Brushing histology is indicated for all types of lung cancer, because in most TBFB-negative cases, biopsies were performed from inappropriate sites of tumors or their materials wer crushed by forceps. It was suggested that concomitant application of brushing specimen for histology examination, contributed to more accurate preoperative histology diagnosis for lung cancer.
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