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  • Title: Wilms' tumour and related syndromes. A unifying theory.
    Author: Côté GB.
    Journal: Ann Genet; 1989; 32(2):69-72. PubMed ID: 2547332.
    Abstract:
    The major role of somatic crossing-over in the aetiology of Wilms' tumour and other forms of cancer is emphasized. A model is proposed to show that tumour development is due to a cis-trans disruptive effect of somatic crossing-over on the maintenance of differential parental imprinting.
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