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  • Title: A fast-responsive mitochondria-targeted fluorescent probe detecting endogenous hypochlorite in living RAW 264.7 cells and nude mouse.
    Author: Xiao H, Xin K, Dou H, Yin G, Quan Y, Wang R.
    Journal: Chem Commun (Camb); 2015 Jan 28; 51(8):1442-5. PubMed ID: 25487031.
    Abstract:
    A very fast-responsive fluorescent probe PZ-Py for imaging mitochondrial HClO/ClO(-), with a relatively long emission wavelength, was prepared. The limit of detection was evaluated to be 17.9 nM. Moreover, the probe PZ-Py was successfully applied in the imaging of endogenous HClO/ClO(-) in the mitochondria of RAW 264.7 cells and living nude mouse.
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