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  • Title: [A comparative study of the biological behavior of gastric cancer from the view of the amount of connective tissue in the cancerous tissue--a correlation between the amount of connective tissue and the metastatic pattern].
    Author: Takakashi Y, Mai M, Ogino T, Ueda H, Ohi A, Sawaguchi K, Asai T, Ohta T, Suga T, Itoh T.
    Journal: Gan No Rinsho; 1989 Aug; 35(9):1011-5. PubMed ID: 2549279.
    Abstract:
    Differences between advanced gastric cancer of the medullary type (med.: 138 cases) and the scirrhous type (sci: 164 cases) with regard to the amount of connective tissue that was cancerous have been studied clinicopathologically. A correlation was found between med and liver metastasis, and sci and peritoneal dissemination in metastatic types, whereas no correlation was observed in other factors except between med and a localized type, sci and infiltrating type in gross type. The study of tumorigenicity in nude mice showed remarkable difference between med (86.7%) and sci. (0%). These results indicate that there is definite relationship between the amount of connective tissue and the biological behavior of a gastric cancer.
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