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Title: FeLV-FAIDS-induced immunodeficiency syndrome in cats. Author: Mullins JI, Hoover EA, Overbaugh J, Quackenbush SL, Donahue PR, Poss ML. Journal: Vet Immunol Immunopathol; 1989 May; 21(1):25-37. PubMed ID: 2549691. Abstract: Findings are reviewed, relevant to elucidation of the pathogenic, genetic and biochemical properties of a single, genetically heterogeneous isolate of feline leukemia virus (FeLV-FAIDS) shown to induce fatal immunodeficiency disease in nearly 100% of inoculated cats. Hypotheses are suggested which pertain to the mechanism of T-cell killing by this virus, and which extrapolate findings in the FeLV-FAIDS animal model to AIDS induced in humans by human immunodeficiency virus (HIV).[Abstract] [Full Text] [Related] [New Search]