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  • Title: Identification of serotype 9 human rotavirus by enzyme-linked immunosorbent assay with monoclonal antibodies.
    Author: Midthun K, Valdesuso J, Kapikian AZ, Hoshino Y, Green KY.
    Journal: J Clin Microbiol; 1989 Sep; 27(9):2112-4. PubMed ID: 2550520.
    Abstract:
    Hybridomas producing monoclonal antibodies to VP7, a major neutralizing protein of serotype 9 rotavirus (strain W161), were prepared. One monoclonal antibody, W161-6A1, was shown to neutralize only serotype 9 rotavirus strains and reacted specifically with serotype 9 rotaviruses in an enzyme-linked immunosorbent assay. The development of an immunoassay for detection of serotype 9 rotaviruses should facilitate epidemiologic studies.
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