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  • Title: Transfusion-related acute lung injury following coronary artery bypass graft surgery.
    Author: Bitargil M, Arslan C, Başbuğ HS, Göçer H, Günerhan Y, Bekov YY.
    Journal: Perfusion; 2015 Nov; 30(8):626-8. PubMed ID: 25575703.
    Abstract:
    Blood transfusion is sometimes a necessary procedure during or following coronary artery bypass graft (CABG) surgery. However, transfusion-related acute lung injury (TRALI)/possible TRALI is a rare and fatal complication and characterized by acute hypoxemia and non-cardiogenic pulmonary edema that occurs within 6 hours following a transfusion. Anti-leukocyte antibodies or, possibly, other bioactive substances cause inflammation and capillary endothelial destruction in susceptible recipients' lungs. Prompt diagnosis and mechanical ventilatory support are important. A successful treatment of two male patients following CABG surgery, compatible with TRALI/possible TRALI, is presented here.
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