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  • Title: [The effect of the stimulation of opioid receptors on lymphocyte functional activity in vivo].
    Author: Kharkevich DD, Kadagidze ZG.
    Journal: Biull Eksp Biol Med; 1989 Sep; 108(9):315-6. PubMed ID: 2558746.
    Abstract:
    With the aid of lymphocytes' spontaneous adhesion test and the reaction of blast transformation with phytohemagglutinin (PHA) the influence of met-enkephaline upon the functional activity of lymphocytes of healthy donors was studied in vitro. It was shown, that met-enkephaline stimulate lymphocyte spontaneous adhesion and the lymphocyte PHA-induced proliferative activity. The stimulating effects of met-enkephalin revealed in vitro were blocked by the opioid receptor blocker naloxone.
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