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  • Title: Antigiardial activity of glycoproteins and glycopeptides from Ziziphus honey.
    Author: Mohammed SE, Kabashi AS, Koko WS, Azim MK.
    Journal: Nat Prod Res; 2015; 29(22):2100-2. PubMed ID: 25587739.
    Abstract:
    Natural honey contains an array of glycoproteins, proteoglycans and glycopeptides. Size-exclusion chromatography fractionated Ziziphus honey proteins into five peaks with molecular masses in the range from 10 to >200 kDa. The fractionated proteins exhibited in vitro activities against Giardia lamblia with IC50 values ≤ 25 μg/mL. Results indicated that honey proteins were more active as antiprotozoal agents than metronidazole. This study indicated the potential of honey proteins and peptides as novel antigiardial agents.
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