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  • Title: Malignant fibrous histiocytoma of sternum: an unusual cause of pyrexia of undetermined origin.
    Author: Grieco A, Caputo S, Silvestri E, Caradonna P, Bertoli A, Greco AV.
    Journal: Postgrad Med J; 1989 Dec; 65(770):926-8. PubMed ID: 2559405.
    Abstract:
    Malignant fibrous histiocytoma of the bone is a very rare tumour mainly affecting long bones, and the most common presenting symptom is local pain. A case of malignant fibrous histiocytoma presenting with pyrexia of undetermined origin and arising in the sternum, a localization not previously described, is reported. The patient died with septic shock after multi-drug chemotherapy including high dose methotrexate treatment with citrovorum factor rescue.
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