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  • Title: Synthesis and biological activity of dansyl thymidines.
    Author: Bonora GM, Palù G, Dos Santos C, Biasolo MA, Meloni GA.
    Journal: Farmaco; 1989 Oct; 44(10):951-8. PubMed ID: 2559740.
    Abstract:
    The synthesis of thymidines selectively dansylated in the 3'- and 5'-positions is reported. The biological investigation showed that these fluorescent nucleosides behave as competitive inhibitors of thymidine kinase (TK) from herpes simplex virus (HSV) and are endowed with a certain degree of antiviral activity against HSV-2 and HSV-1.
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