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Title: Generation and characterization of a human monoclonal antibody against phenolic glycolipid-I of M. leprae. Author: Moudgil KD, Gupta SK, Talwar GP. Journal: Indian J Lepr; 1989 Oct; 61(4):479-84. PubMed ID: 2559933. Abstract: The development of an Epstein-Barr virus transformed human B-cell line secreting a monoclonal antibody (MoAb), KR2/B5 is described. KR2/B5 is an IgM type of antibody and is highly specific for phenolic glycolipid-I (PGL-I) a component unique to M. leprae. The MoAb appears to be directed against the terminal sugar residue of the immunodominant trisaccharide component of PGL-I.[Abstract] [Full Text] [Related] [New Search]