These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Ethnic-specific cut-points for sarcopenia: evidence from black South African women.
    Author: Kruger HS, Micklesfield LK, Wright HH, Havemann-Nel L, Goedecke JH.
    Journal: Eur J Clin Nutr; 2015 Jul; 69(7):843-9. PubMed ID: 25604775.
    Abstract:
    BACKGROUND/OBJECTIVES: Age-related muscle and fat mass (FM) changes are ethnicity specific. We aimed to develop a cut-point for the muscle mass component of sarcopenia for black South African (SA) women, and to assess its predictive value, in comparison to established cut-points, to identify functional ability among older black SA women. SUBJECTS/METHODS: In a cross-sectional study, a sarcopenia cut-point was calculated from dual energy X-ray absorptiometry (DXA)-derived appendicular skeletal muscle mass (ASM) indexes (ASMI) from two young black SA reference groups. The new cut-point was compared with the most recent Foundation for the National Institutes of Health (FNIH) criteria (ASM <15.02 kg; and ASM(BMI) <0.512), an internationally accepted cut-point (ASMI <5.5 kg/m(2)) and a residual method adjusting for FM. All cut-points were then applied to 221 older black women to predict gait speed and handgrip strength. RESULTS: A cut-point of ASMI <4.94 kg/m(2) was derived from the young SA reference groups. Using this cut-point, 9.1% of older women were classified as sarcopenic, compared with 16.7-38.7% using other cut-points. The only cut-points that significantly predicted low functional ability (low gait speed and low handgrip strength) in older black women were the new SA cut-point and the FNIH ASM criterion. Multivariate logistic regression models for both these cut-points significantly predicted low handgrip strength (odds ratio (OR)=3.71, P=0.007 and OR=3.42, P=0.001, respectively) and low gait speed (OR=9.82, P=0.004 and OR=8.71, P=0.008, respectively). CONCLUSIONS: The new SA cut-point had similar or greater odds of predicting reduced functional ability in older SA women when compared with other internationally accepted cut-points.
    [Abstract] [Full Text] [Related] [New Search]