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  • Title: [The role of single-stranded DNA in the integration of SV40 genome into cellular DNA].
    Author: Popov LS.
    Journal: Biokhimiia; 1989 Nov; 54(11):1815-20. PubMed ID: 2560669.
    Abstract:
    The integration of temperature-sensitive SV40 mutant DNA (tsA239) into the Chinese hamster cellular genome at an early stage of infection was studied. The content of single-stranded DNA structures in the infected and control cells at a non-permissive temperature (40 degrees C) differed drastically from that in control cells at permissive temperatures (33 degrees C, 37 degrees C). The role of single-stranded structures in the integration of the SV40 genome into cellular DNA was shown by blot hybridization. The integration mechanism is discussed.
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