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  • Title: Towards model-based adaptive optics optical coherence tomography.
    Author: Verstraete HR, Cense B, Bilderbeek R, Verhaegen M, Kalkman J.
    Journal: Opt Express; 2014 Dec 29; 22(26):32406-18. PubMed ID: 25607203.
    Abstract:
    The transfer function for optical wavefront aberrations in single-mode fiber based optical coherence tomography is determined. The loss in measured OCT signal due to optical wavefront aberrations is quantified using Fresnel propagation and the calculation of overlap integrals. A distinction is made between a model for a mirror and a scattering medium model. The model predictions are validated with measurements on a mirror and a scattering medium obtained with an adaptive optics optical coherence tomography setup. Furthermore, a one-step defocus correction, based on a single A-scan measurement, is derived from the model and verified. Finally, the pseudo-convex structure of the optical coherence tomography transfer function is validated with the convergence of a hill climbing algorithm. The implications of this model for wavefront sensorless aberration correction are discussed.
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