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  • Title: Argonautes team up to silence transposable elements in Arabidopsis.
    Author: Underwood CJ, Martienssen RA.
    Journal: EMBO J; 2015 Mar 04; 34(5):579-80. PubMed ID: 25630704.
    Abstract:
    The de novo silencing of transposable elements in plants and animals is mediated in part by RNA-directed chromatin modification. In flowering plants, AGO4 has been seen as the key argonauteprotein in the RNA-directed DNA methylation pathway that links the plant-specific RNA polymerase V with the de novo DNA methyltransferase DRM2 (Zhong et al,2014). Two recent papers in The EMBO Journal strongly implicate a role for the AGO6 protein in the process of de novo silencing.
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