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  • Title: Presynaptic effects of spider toxins: increase of high affinity uptake in the arthropod peripheral glutamatergic system.
    Author: van Marle J, Piek T, Karst H, Lind A, van Weeren-Kramer J.
    Journal: Experientia; 1989 Feb 15; 45(2):155-6. PubMed ID: 2563978.
    Abstract:
    In contrast to the reported effects of polyamines on the high affinity neurotransmitter uptake, two polyamine-like spider toxins significantly increase the high affinity uptake of glutamate as demonstrated with high resolution autoradiography. The effects of both spider toxins were compared to those of a polyamine toxin from the wasp Philanthus triangulum, which is known to inhibit the high affinity glutamate uptake.
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