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  • Title: Multifunctional self-assembled polymeric nanoprobes for FRET-based ratiometric detection of mitochondrial H2O2 in living cells.
    Author: Qiao J, Liu Z, Tian Y, Wu M, Niu Z.
    Journal: Chem Commun (Camb); 2015 Feb 28; 51(17):3641-4. PubMed ID: 25642908.
    Abstract:
    A ratiometric, multifunctional nanoprobe was prepared consisting of a self-assembled polymeric micelle as the carrier, tetraphenylethene (TPE) as the donor, fluorescent boronate as the H2O2-responsive acceptor, and triphenylphosphonium as a mitochondria-targeted moiety. The assembled nanoparticles could detect both exogenous and endogenous mitochondrial H2O2 changes in living cells.
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