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  • Title: [Neonatal seizures: consider sinus thrombosis].
    Author: Brandhoff J, de Vries LS, Smal JC.
    Journal: Ned Tijdschr Geneeskd; 2015; 159():A8055. PubMed ID: 25650028.
    Abstract:
    Cerebral sinovenous thrombosis is a possible cause of neonatal seizures. It can be demonstrated by neuroradiological Doppler ultrasound or MRI/MRV. Maternal, perinatal and neonatal factors all contribute to the development of sinovenous thrombosis. It is important to identify these factors and, if necessary and possible, to start treatment. Anticoagulation therapy should be considered when sinovenous thrombosis is diagnosed. Long-term follow-up is needed in these children, as they run a substantial risk of developing postneonatal epilepsy (ESES) and of poorer developmental outcomes.
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