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  • Title: Neuroleptic-valproic acid combination in treatment of psychotic symptoms: a three-case report.
    Author: Wassef A, Watson DJ, Morrison P, Bryant S, Flack J.
    Journal: J Clin Psychopharmacol; 1989 Feb; 9(1):45-8. PubMed ID: 2565347.
    Abstract:
    Valproic acid is infrequently used for treatment of psychosis. Three consecutive patients with severe neuroleptic-resistant psychotic symptoms responded dramatically to the combination of valproic acid and neuroleptics. All three had normal EEGs and CT scans. Outpatient follow-up showed that the combination was effective in maintaining remissions.
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