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  • Title: Partially Plexiform Neurofibroma of the Labia Minora and Clitoral Hood-A Prognostic Dilemma.
    Author: Wehmeijer LM, Hage JJ, Eberz B, van Beurden M.
    Journal: J Low Genit Tract Dis; 2015 Jul; 19(3):e55-7. PubMed ID: 25658713.
    Abstract:
    BACKGROUND: Unlike solitary neurofibromas, neurofibromatosis type 1 (NF1 or von Recklinghausen disease) has been associated with an increased risk of malignancies. Differentiation between these 2 entities may not be straightforward. CASE REPORT: We present the exceptional case of a girl with one congenital plexiform neurofibroma of the labia minora and clitoral hood in whom the diagnosis NF1 could not been made. Although this presented a prognostic dilemma, we advised against a screening program for any of the malignancies associated with NF1. Still, long-term follow-up seems indicated for recurrence of the partially plexiform neurofibroma and a possible occurrence of malignant peripheral nerve sheath tumor.
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