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  • Title: [Loprazolam: a new imidazobenzodiazepine for the treatment of insomnia].
    Author: Pallarés M.
    Journal: Actas Luso Esp Neurol Psiquiatr Cienc Afines; 1989; 17(1):49-52. PubMed ID: 2566256.
    Abstract:
    Loprazolam is a 1,4-benzodiazepine with hypnotics properties, useful for acute or chronic insomnia. His half-life of 7 to 8 hours in healthy adults, it may have advantages over benzodiazepines of short and longer-acting hypnotics. Although Loprazolam has been shown to have anti-anxiety, anticonvulsant and muscle relaxant effects, a longer acting benzodiazepine may be more appropriate when this prolonged effects is desired. Loprazolam would appear how a effective hypnotic with minimal side effects, which come to cover a place between the benzodiazepines with short and long half-life.
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