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  • Title: Serological response to P-fimbriae of Escherichia coli in patients with urinary tract infections.
    Author: Agata N, Ohta M, Miyazawa H, Mori M, Kido N, Kato N.
    Journal: Eur J Clin Microbiol Infect Dis; 1989 Feb; 8(2):156-9. PubMed ID: 2566483.
    Abstract:
    The antibody response to P-fimbriae of Escherichia coli in patients with upper urinary tract infections was investigated. In the sera of patients with pyelonephritis obtained at the initial visit to hospital (3 to 7 days after the onset of symptoms), a high incidence of antibodies to P-fimbriae was detected (12 out of 14 patients). P-fimbriated Escherichia coli strains were isolated from urine samples in all of these antibody-positive patients. Antibodies detected by ELISA using purified antigen were essentially IgG and specifically recognized P-fimbriae. These antibodies inhibited completely, or in some cases partially, mannose-resistant hemagglutination with P-fimbriated Escherichia coli.
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