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  • Title: Seven new drimane-type sesquiterpenoids from cultures of fungus Laetiporus sulphureus.
    Author: He JB, Tao J, Miao XS, Bu W, Zhang S, Dong ZJ, Li ZH, Feng T, Liu JK.
    Journal: Fitoterapia; 2015 Apr; 102():1-6. PubMed ID: 25665943.
    Abstract:
    Seven new drimane-type sesquiterpenoids, sulphureuines B-H (1-7), together with four known compounds (8-11), were obtained from cultures of mushroom Laetiporus sulphureus. All of these compounds were tested for their cytotoxicities against five human cancer cell lines (HL-60, SMMC-721, A-549, MCF-7, SW-480), compound 10 showed potent cytotoxic activity against HL-60, SMMC-721, A-549, SW-480, with IC50 values of 37.5, 14.8, 15.6, and 36.1μM, respectively.
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