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  • Title: Sublingual misoprostol is as effective as intravenous oxytocin to reduce intra-operative blood loss during cesarean delivery in women living at high altitude.
    Author: Gavilanes P, Morales MF, Velasco S, Teran E.
    Journal: J Matern Fetal Neonatal Med; 2016; 29(4):559-61. PubMed ID: 25666740.
    Abstract:
    OBJECTIVE: To assess the effect of sublingual misoprostol compared to intravenous oxytocin for blood loss during cesarean delivery in women living at high altitude. STUDY DESIGN: In a randomized trial, conducted in Quito, Ecuador (2800 m above sea level), 100 women received either sublingual misoprostol (400 µg) or intravenous oxytocin (10 IU). RESULTS: Bleeding in the misoprostol was no different than in the oxytocin group. Shivering was reported in 66% of women in the misoprostol group. CONCLUSION: Sublingual misoprostol might be a valid alternative to oxytocin reduce intra-operative blood loss during cesarean section in women living at high altitude.
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