These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Determination of growth hormone: comparison between a physiologic stimulus (exercise) and pharmacologic stimuli (clonidine/guanfacine)].
    Author: García Ruiz ML, Rodríguez Arnao MD, Lorenzo Navarro L, Mancheño Rico E, Teruel de Francisco MC, Gómez Pan A.
    Journal: An Esp Pediatr; 1989 Mar; 30(3):163-5. PubMed ID: 2567140.
    Abstract:
    We have compared the release of growth hormone (GH) after exercise (10 minutes pedaling on a fixed bicycle with ergometer), and two pharmacological alpha-adrenergic stimuli: clonidine (CL) or guanfacine (GU); in 36 prepuberal children whose height was below the third percentile. The tests were carried out in basal conditions, randomized and with a minimum interval of seven days between them. Blood GH was determined from cannulated antecubital veins. The results show a positive response (GH greater than 7 ng/ml) in 65.7% of cases after exercise, in 74.2% after CL and 71% after GU. The significant secondary effects observed after CL administration were sleepiness and decrease of arterial pressure. It is concluded that exercise is a useful test for assessing a possible deficiency of GH, and lacks significant side effects and that the diagnostic value of GU is similar to that of CL.
    [Abstract] [Full Text] [Related] [New Search]