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  • Title: Primary Aspergillus sellar abscess simulating pituitary tumor in immunocompetent patient.
    Author: Ouyang T, Zhang N, Wang L, Jiao J, Zhao Y, Li Z, Chen J.
    Journal: J Craniofac Surg; 2015 Mar; 26(2):e86-8. PubMed ID: 25675014.
    Abstract:
    A 55-year-old woman presented with headache, dizziness, and decreased visual acuity. Magnetic resonance imaging revealed a sellar mass with sphenoid sinus extension. The result of hormone showed an obviously high prolactin (815 ng/mL). The mass was resected and diagnosed with aspergillosis pathologically. Postoperatively, the level of prolactin dramatically decreased, and the patient received medical treatment with voriconazole and caspofungin. During a 6-month follow-up, the patient's headache and dizziness disappeared, and visual acuity improved. Therefore, aspergillus sellar abscess could result in hyperprolactinemia and should be considered in the differential diagnosis of a sellar mass, even in immunocompetent patients. A combination of surgery and antifungal therapy could reduce the hyperprolactinemia and improve symptoms.
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