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  • Title: Pharmacokinetics of iotrolan after intravenous injection into healthy volunteers.
    Author: Scholz P, Weinmann HJ, Mützel W, Staks T.
    Journal: Fortschr Geb Rontgenstrahlen Nuklearmed Erganzungsbd; 1989; 128():211-4. PubMed ID: 2568798.
    Abstract:
    In man Iotrolan is distributed in the extravascular space after intravenous injection with a half-life of about 11 minutes, the elimination half-life being about 108 minutes. After intravenous injection 99.2 +/- 1.8% of the dose was found in the urine and 0.5 +/- 0.1% in the feces within 5 days. No metabolization occurred in man and the pharmacokinetic behavior of iotrolan is comparable to that of known nonionic contrast media (e.g., iohexol, iopromide) (7, 9, 13).
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