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  • Title: [Circadian rhythms of mineral-excreting kidney function in healthy persons and their changes in ischemic heart disease].
    Author: Aslanian NL, Babaian LA, Asatrian MA, Krishchian EM, Gabrielian RS.
    Journal: Ter Arkh; 1989; 61(4):45-8. PubMed ID: 2569774.
    Abstract:
    Seventy normal persons and 100 patients with coronary disease were examined for circadian rhythms of urine and minerals excretion. The data obtained demonstrate that normal persons were characterized by circadian rhythms of urine and minerals excretion with a definite confidence interval of mesor and amplitude fluctuations. Angina pectoris of effort was marked by infradian rhythms of mineral excreting renal function. Monotherapy with beta-blockers or calcium antagonists given in courses entailed the recovery of the circadian rhythms of mineral-excreting renal function. Parameters of the rhythms of urine and minerals excretion in patients with angina pectoris of effort and rest noticeably differed from those in patients with angina pectoris of effort. In 30.7 percent of the persons, the use of the mathematic methods did not reveal any significant rhythms. The circadian range was found to predominate among the significant rhythms. Antianginal treatment did not produce any appreciable changes.
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